Vitamin B12 Deficiency 

Learn how a Vitamin B12 Deficiency or problems associated with a Vitamin B12 Deficiency can affect you.

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About Vitamin B12 Deficiency

Herbal Supplements

B₁₂ is mostly absorbed in the terminal ileum. The production of intrinsic factor in the stomach is vital to absorption of this vitamin. Megaloblastic anemia can result from inadequate intake of B₁₂, inadequate production of intrinsic factor (pernicious anemia), disorders of the terminal ileum resulting in malabsorption, or by competition for available B₁₂ (such as fish tapeworms or bacteria present in blind loop syndrome). Neurological signs of vitamin b12 deficiency, which can occur without accompanying hematologic abnormalities, include demyelination and irreversible nerve cell death. Symptoms include numbness or tingling of the extremities and an ataxic gait.

The American Psychiatric Association's American Journal of Psychiatry has published studies showing a relationship between depression levels ,vitamin b12 deficiency and blood levels in elderly people .

Traditionally, treatment for vitamin b12 deficiency was through intramuscular injections of cyanocobalamin. However, it has recently been appreciated that deficiency can be treated with oral B₁₂ supplements when given in sufficient doses. The usual daily intake in the Western diet is 5-7 mcg. However, when given in oral doses ranging from 1000-2000 mcg daily, B₁₂ can be absorbed in a pathway that does not require an intact ileum or intrinsic factor.The Schilling test can determine whether symptoms of B₁₂ deficiency are caused by lack of intrinsic factor, though this is being performed less often due to the lack of availability of reagent for the test.

(c) vitamin b12 deficiency